Active not recruiting
A Study of Solanezumab in Older Participants Who May be at Risk for Memory Loss (A4)
H8A-MC-LZAZ - ClinicalTrials.gov - NCT02008357
The purpose of this study is to test whether an investigational drug called solanezumab can slow the progression of memory problems associated with brain amyloid (protein that forms plaques in the brains of people with Alzheimer Disease [AD]).
How long will I be in the trial?
Your participation could last approximately 4 1/2 years and include 66 visits to the study center
Active not recruiting
A Study of Solanezumab in Older Participants Who May be at Risk for Memory Loss (A4)
H8A-MC-LZAZ - ClinicalTrials.gov - NCT02008357
The purpose of this study is to test whether an investigational drug called solanezumab can slow the progression of memory problems associated with brain amyloid (protein that forms plaques in the brains of people with Alzheimer Disease [AD]).
How long will I be in the trial?
Your participation could last approximately 4 1/2 years and include 66 visits to the study center
Key Requirements
Age :
65-85
Sex:
All
Key Requirements
Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.
Age
65-85
Sex
All
Participants must
Participant must have a study partner that is willing to participate as a source of information and has at least weekly contact with the participant (contact can be in-person, via telephone or electronic communication)
Participant must have good vein access, such that intravenous (IV) drug delivery or multiple blood draws would be able to be obtained
Participants must NOT
Participant must not be receiving a prescription acetylcholinesterase inhibitor (AChEI) and/or memantine
Participant must not have a history within the last 5 years of a serious infectious disease affecting the brain (including neurosyphilis, meningitis, or encephalitis) or head trauma resulting in longer than expected loss of consciousness
Participant must not have a history within the past 2 years of major depression or bipolar disorder
Participant must not have a history within the past 5 years of chronic alcohol or drug abuse/dependence
Participant must not have a known history of human immunodeficiency virus (HIV)
Trial Summary
Conditions the trial is for
At Risk For Alzheimer's
What the trial is testing?
Solanezumab (LY2062430), Placebo
Could I receive a Placebo?
yes
Enrollment Goal
1150
Trial Dates
February 2014 - July 2022
Trial Phase
3
Enter your postal code to find the nearest site
Key Requirements
Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.
Age
65-85
Sex
All
Participants must
Participant must have a study partner that is willing to participate as a source of information and has at least weekly contact with the participant (contact can be in-person, via telephone or electronic communication)
Participant must have good vein access, such that intravenous (IV) drug delivery or multiple blood draws would be able to be obtained
Participants must NOT
Participant must not be receiving a prescription acetylcholinesterase inhibitor (AChEI) and/or memantine
Participant must not have a history within the last 5 years of a serious infectious disease affecting the brain (including neurosyphilis, meningitis, or encephalitis) or head trauma resulting in longer than expected loss of consciousness
Participant must not have a history within the past 2 years of major depression or bipolar disorder
Participant must not have a history within the past 5 years of chronic alcohol or drug abuse/dependence
Participant must not have a known history of human immunodeficiency virus (HIV)
Trial Summary
Conditions the trial is for
At Risk For Alzheimer's
What the trial is testing?
Solanezumab (LY2062430), Placebo
Could I receive a Placebo?
yes
Enrollment Goal
1150
Trial Dates
February 2014 - July 2022
Trial Phase
3
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Trial Locations
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