Recruiting

A Donanemab (LY3002813) Prevention Study in Participants With Alzheimer's Disease (TRAILBLAZER-ALZ 3)

I5T-MC-AACM - ClinicalTrials.gov - NCT05026866

The main purpose of this study is to evaluate the safety and efficacy of donanemab in participants with preclinical Alzheimer's Disease (AD).
How long will I be in the trial?
Your participation could last up to 186 weeks + and include up to 17 visits to the study center.
Email
Recruiting

A Donanemab (LY3002813) Prevention Study in Participants With Alzheimer's Disease (TRAILBLAZER-ALZ 3)

I5T-MC-AACM - ClinicalTrials.gov - NCT05026866

The main purpose of this study is to evaluate the safety and efficacy of donanemab in participants with preclinical Alzheimer's Disease (AD).
How long will I be in the trial?
Your participation could last up to 186 weeks + and include up to 17 visits to the study center.
Email

Key Requirements

Age :

55-80

Sex:

All

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

55-80

Sex

All

Participants must

Participant must have a reliable study partner with whom they have regular contact and who can be contacted during the study

Participants must NOT

Participants must not have been diagnosed with a condition that causes memory or thinking problems such as dementia or early dementia, or a significant disease of the brain

Participants must not have a serious medical condition, such as a neurologic or psychiatric illness, or a history of a serious medical condition, including certain types of cancers

Participants must not have a history of severe drug allergies or hypersensitivity reactions

Participants must not have any allergies to Donanemab or its components

Participants must not have certain health conditions that prevent them from getting an MRI

Participants must not have certain abnormal lab or MRI values at screening

Participants must not have taken certain medicines or had certain treatments

Participant must not be pregnant or can become pregnant during the study (for example, have not had menopause or ovary removal)

Trial Summary

Conditions the trial is for

Early Symptoms of Alzheimer's Disease, At Risk For Alzheimer's

What the trial is testing?

Donanemab, LY3002813

Could I receive a Placebo?

yes

Enrollment Goal

3300

Trial Dates

August 2021 - November 2027

Trial Phase

3

Enter your postal code to find the nearest site

Think this trial might be a good fit for you?

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

55-80

Sex

All

Participants must

Participant must have a reliable study partner with whom they have regular contact and who can be contacted during the study

Participants must NOT

Participants must not have been diagnosed with a condition that causes memory or thinking problems such as dementia or early dementia, or a significant disease of the brain

Participants must not have a serious medical condition, such as a neurologic or psychiatric illness, or a history of a serious medical condition, including certain types of cancers

Participants must not have a history of severe drug allergies or hypersensitivity reactions

Participants must not have any allergies to Donanemab or its components

Participants must not have certain health conditions that prevent them from getting an MRI

Participants must not have certain abnormal lab or MRI values at screening

Participants must not have taken certain medicines or had certain treatments

Participant must not be pregnant or can become pregnant during the study (for example, have not had menopause or ovary removal)

Trial Summary

Conditions the trial is for

Early Symptoms of Alzheimer's Disease, At Risk For Alzheimer's

What the trial is testing?

Donanemab, LY3002813

Could I receive a Placebo?

yes

Enrollment Goal

3300

Trial Dates

August 2021 - November 2027

Trial Phase

3

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Trial Locations

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Resources

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Clinical Trial Participation: What to Expect

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study in people that helps to determine if and how a drug or therapy works. These can also be called clinical studies, or clinical research. Clinical research helps us answer specific questions about an investigational drug , such as: Is it effective? Is it more effective than another established treatment? Is it safe and/or what are its side effects?