A Study of Prexasertib (LY2606368) With Chemotherapy or Targeted Agents in Participants With Advanced Cancer

The main purpose of this study is to investigate the safety of prexasertib in combination with other anti-cancer drugs (cisplatin, cetuximab, pemetrexed, fluorouracil or LY3023414) in participants with advanced cancer or cancer that has spread to another part of the body. The study has multiple parts (A, B, C, D and E). Participants will only enroll in one part.

Trial Summary

Age Range
≥18 years
Conditions the trial is for
Advanced Cancer
What the trial is testing?
Cetuximab, Leucovorin , Samotolisib, Fluorouracil, Pemetrexed, G-CSF, Prexasertib, Cisplatin
Could I receive a Placebo?
No
Enrollment Goal
167
Trial Dates
Jun 18, 2014 - Feb 13, 2020
How long will I be in the trial?
Your participation may continue for as long as you and your study doctor feel that you are benefiting from the study treatment.
Trial Phase
I

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