Recruiting

A Study of LY3405105 in Participants With Advanced Cancer

J1F-MC-JZFA - ClinicalTrials.gov - NCT03770494

The main purpose of this study is to investigate the safety of LY3405105 in participants with advanced cancer. The study has two parts phase 1a and phase 1b. Participants will only enroll in one part.
How long will I be in the trial?
Your participation in this trial could last 6 months or longer depending on how you and your tumor respond.
Email
Recruiting

A Study of LY3405105 in Participants With Advanced Cancer

J1F-MC-JZFA - ClinicalTrials.gov - NCT03770494

The main purpose of this study is to investigate the safety of LY3405105 in participants with advanced cancer. The study has two parts phase 1a and phase 1b. Participants will only enroll in one part.
How long will I be in the trial?
Your participation in this trial could last 6 months or longer depending on how you and your tumor respond.
Email

Key Requirements

Age :

18+

Sex:

All

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

All

Participants must

Participants must have evidence of a diagnosis of a solid tumor cancer that is advanced and/or metastatic

Participants must have available archived tissue for exploratory biomarker analysis

Participants must have adequate organ function

Participants must have discontinued all previous treatments for cancer and recovered from their side effects

Participants must be able to swallow capsules/tablets

Participants must NOT

Participants must not have symptomatic central nervous system (CNS) malignancy or metastasis

Participants must not have symptomatic HIV, Hepatitis A, B, or C

Participants must not have congestive heart failure

Participants must not be breastfeeding

Trial Summary

Conditions the trial is for

Advanced Cancer

What the trial is testing?

LY3405105

Could I receive a Placebo?

no

Enrollment Goal

180

Trial Dates

January 2019 - June 2021

Trial Phase

1

Enter your postal code to find the nearest site

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

All

Participants must

Participants must have evidence of a diagnosis of a solid tumor cancer that is advanced and/or metastatic

Participants must have available archived tissue for exploratory biomarker analysis

Participants must have adequate organ function

Participants must have discontinued all previous treatments for cancer and recovered from their side effects

Participants must be able to swallow capsules/tablets

Participants must NOT

Participants must not have symptomatic central nervous system (CNS) malignancy or metastasis

Participants must not have symptomatic HIV, Hepatitis A, B, or C

Participants must not have congestive heart failure

Participants must not be breastfeeding

Trial Summary

Conditions the trial is for

Advanced Cancer

What the trial is testing?

LY3405105

Could I receive a Placebo?

no

Enrollment Goal

180

Trial Dates

January 2019 - June 2021

Trial Phase

1

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Trial Locations

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Advanced Cancer Resources

Clinical Trial Participation: What to Expect

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study in people that helps to determine if and how a drug or therapy works. These can also be called clinical studies, or clinical research. Clinical research helps us answer specific questions about an investigational drug , such as: Is it effective? Is it more effective than another established treatment? Is it safe and/or what are its side effects?