Enrolling

A Study of Selpercatinib After Surgery or Radiation in Participants With Non-Small Cell Lung Cancer (NSCLC) (LIBRETTO-432)

J2G-MC-JZJX -

The reason for this study is to see if the study drug, selpercatinib, compared to placebo, is effective and safe in delaying cancer return in participants with early-stage non-small cell lung cancer (NSCLC), who have already had surgery or radiation. Participants who are assigned to placebo and stop the study drug because their disease comes back or gets worse have the option to potentially crossover to selpercatinib.

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See if You May Qualify

Answer a few questions to see if you meet key criteria for this study.

Trial Summary

Age Range
≥18 years
Conditions the trial is for
Non-Small Cell Lung Cancer
What the trial is testing?
Selpercatinib
Could I receive a Placebo?
Yes
Enrollment Goal
170
Trial Dates
Dec 20, 2021 - Aug 2032
How long will I be in the trial?
Participation could last up to three years.
Trial Phase
III

Key Requirements

Clinical trials have inclusion and exclusion requirements to determine which individuals qualify for participation. Listed below are key requirements for this clinical trial, but there may be additional requirements to qualify.

Participants Must:

  • Participants must have early-stage non-small cell lung cancer (NSCLC)

  • Participants must have already had (and recovered from) surgery or radiation

  • Participants must be in fair to good health

  • Participants must be willing to use highly effective birth control during the study

Participants Must Not:

  • Participants must not have another serious medical condition

  • Participants must not have disease that has spread

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Take the Next Step

Complete this Lilly Trial Connect questionnaire to find out if this clinical trial may be a good fit for you, or a loved one.
When you press Start Lilly Trial Connect, you will answer questions about relevant medical conditions and treatment history. The answers will be compared to some of the key criteria for this trial, called inclusion and exclusion criteria.

If your responses show that the trial may be a good fit, you can:
  • Select which clinical trial site works best for you.
  • Share your details and questionnaire directly with site(s) that allow this.
  • Get contact details for the site(s) of your choice.

Completing the Trial Connect questionnaire doesn’t mean that you will be enrolled in a study. There may be more eligibility criteria for the study which are assessed by the Lilly clinical team.

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