Completed

A Study of Tirzepatide (LY3298176) Versus Insulin Degludec in Participants With Type 2 Diabetes

I8F-MC-GPGH - ClinicalTrials.gov - NCT03882970

The purpose of this study is to compare the effect of the study drug tirzepatide to insulin degludec on blood sugar levels in participants with type 2 diabetes.
How long will I be in the trial?
The study will last about 59 weeks and may include up to 22 visits.
Email
Completed

A Study of Tirzepatide (LY3298176) Versus Insulin Degludec in Participants With Type 2 Diabetes

I8F-MC-GPGH - ClinicalTrials.gov - NCT03882970

The purpose of this study is to compare the effect of the study drug tirzepatide to insulin degludec on blood sugar levels in participants with type 2 diabetes.
How long will I be in the trial?
The study will last about 59 weeks and may include up to 22 visits.
Email

Key Requirements

Age :

18+

Sex:

All

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

All

Participants must

Participant must have type 2 diabetes mellitus (T2DM)

Participant must be on stable treatment dose of metformin, with or without an SGLT-2 inhibitor

Participant must be of stable weight

Participants must NOT

Participant must not have type 1 diabetes mellitus (T1DM)

Participant must not have pancreatitis

Participant must not have disorders with slowed emptying of the stomach contents, or have had any stomach surgeries for the purpose of weight loss

Participant must not have acute or chronic hepatitis or symptoms of any other liver disease

Participant must not have had a heart attack stroke, or hospitalization for congestive heart failure in the past 2 months

Participant must not have been taking weight loss drugs including over-the-counter medications during the last 3 months

Trial Summary

Conditions the trial is for

Adult Type 2 Diabetes

What the trial is testing?

Tirzepatide, Insulin Degludec

Could I receive a Placebo?

no

Enrollment Goal

1420

Trial Dates

April 2019 - January 2021

Trial Phase

3

Enter your postal code to find the nearest site

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

All

Participants must

Participant must have type 2 diabetes mellitus (T2DM)

Participant must be on stable treatment dose of metformin, with or without an SGLT-2 inhibitor

Participant must be of stable weight

Participants must NOT

Participant must not have type 1 diabetes mellitus (T1DM)

Participant must not have pancreatitis

Participant must not have disorders with slowed emptying of the stomach contents, or have had any stomach surgeries for the purpose of weight loss

Participant must not have acute or chronic hepatitis or symptoms of any other liver disease

Participant must not have had a heart attack stroke, or hospitalization for congestive heart failure in the past 2 months

Participant must not have been taking weight loss drugs including over-the-counter medications during the last 3 months

Trial Summary

Conditions the trial is for

Adult Type 2 Diabetes

What the trial is testing?

Tirzepatide, Insulin Degludec

Could I receive a Placebo?

no

Enrollment Goal

1420

Trial Dates

April 2019 - January 2021

Trial Phase

3

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Trial Locations

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Adult Type 2 Diabetes Resources

Clinical Trial Participation: What to Expect

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study in people that helps to determine if and how a drug or therapy works. These can also be called clinical studies, or clinical research. Clinical research helps us answer specific questions about an investigational drug , such as: Is it effective? Is it more effective than another established treatment? Is it safe and/or what are its side effects?