Recruiting

A Study of LY3561774 in Participants With Dyslipidemia.

J3F-MC-EZCA - ClinicalTrials.gov - NCT04644809

This is a 3-part study. In Parts A and B, the main purpose is to evaluate the safety and tolerability of the study drug known as LY3561774 in participants with dyslipidemia (high blood fat levels). How the body processes the study drug and the effect of the study drug on blood fat levels will also be investigated. Part C will mainly evaluate the safety and tolerability of LY3561774 as well as how the body processes the study drug in Japanese participants.
How long will I be in the trial?
The study may last up 52, 56 and 28 weeks for each participant in Parts A, B and C, respectively. There are up to 22, 26 and 16 visits in Parts A, B and C, respectively.
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Recruiting

A Study of LY3561774 in Participants With Dyslipidemia.

J3F-MC-EZCA - ClinicalTrials.gov - NCT04644809

This is a 3-part study. In Parts A and B, the main purpose is to evaluate the safety and tolerability of the study drug known as LY3561774 in participants with dyslipidemia (high blood fat levels). How the body processes the study drug and the effect of the study drug on blood fat levels will also be investigated. Part C will mainly evaluate the safety and tolerability of LY3561774 as well as how the body processes the study drug in Japanese participants.
How long will I be in the trial?
The study may last up 52, 56 and 28 weeks for each participant in Parts A, B and C, respectively. There are up to 22, 26 and 16 visits in Parts A, B and C, respectively.
Email

Key Requirements

Age :

18-65

Sex:

All

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18-65

Sex

All

Participants must

Participants must have high blood fat levels for Part A and B

Participants must be first generation Japanese origin for Part C

Participants must have a body mass index (BMI) of 18.5 to 40.0 kilograms per square meter (kg/m²)

Male participants must agree to adhere to contraception restrictions and female participants must not be able to get pregnant

Participants must NOT

Participants must not have taken any prescription medications that are for blood fat lowering within the past 2 months (use of statins is allowed if the dose has been stable for 8 weeks)

Participants must not have Type 1 diabetes

Participants must not have currently participated in or completed a clinical trial within the last 30 days

Participants must not be a heavy alcohol drinker or heavy cigarette smoker

Participants must not have donated blood of more than 500 milliliters (mL) in the last 3 months

Trial Summary

Conditions the trial is for

Dyslipidemia

What the trial is testing?

LY3561774

Could I receive a Placebo?

yes

Enrollment Goal

74

Trial Dates

November 2020 - April 2022

Trial Phase

1

Enter your postal code to find the nearest site

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18-65

Sex

All

Participants must

Participants must have high blood fat levels for Part A and B

Participants must be first generation Japanese origin for Part C

Participants must have a body mass index (BMI) of 18.5 to 40.0 kilograms per square meter (kg/m²)

Male participants must agree to adhere to contraception restrictions and female participants must not be able to get pregnant

Participants must NOT

Participants must not have taken any prescription medications that are for blood fat lowering within the past 2 months (use of statins is allowed if the dose has been stable for 8 weeks)

Participants must not have Type 1 diabetes

Participants must not have currently participated in or completed a clinical trial within the last 30 days

Participants must not be a heavy alcohol drinker or heavy cigarette smoker

Participants must not have donated blood of more than 500 milliliters (mL) in the last 3 months

Trial Summary

Conditions the trial is for

Dyslipidemia

What the trial is testing?

LY3561774

Could I receive a Placebo?

yes

Enrollment Goal

74

Trial Dates

November 2020 - April 2022

Trial Phase

1

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Trial Locations

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Dyslipidemia Resources

Clinical Trial Participation: What to Expect

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study in people that helps to determine if and how a drug or therapy works. These can also be called clinical studies, or clinical research. Clinical research helps us answer specific questions about an investigational drug , such as: Is it effective? Is it more effective than another established treatment? Is it safe and/or what are its side effects?