Active not recruiting

A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Preventing SARS-CoV-2 Infection and COVID-19 in Nursing Home Residents and Staff (BLAZE-2)

J2X-MC-PYAD - ClinicalTrials.gov - NCT04497987

The purpose of this study is to evaluate whether LY3819253 given alone and with LY3832479 prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease – 2019 (COVID-19) in facility staff and residents in skilled nursing and assisted living facilities with a high risk of SARS-CoV-2 exposure. Participants with a high risk of SARS-CoV-2 exposure will receive LY3819253, LY3819253 and LY3832479, or placebo via an injection into a vein. Samples will be taken from the nose. Blood samples will be drawn. To speak with a study representative, call 718-210-9713.
How long will I be in the trial?
Participation could last up to 25 weeks and may include up to 19 visits.
Email
Active not recruiting

A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Preventing SARS-CoV-2 Infection and COVID-19 in Nursing Home Residents and Staff (BLAZE-2)

J2X-MC-PYAD - ClinicalTrials.gov - NCT04497987

The purpose of this study is to evaluate whether LY3819253 given alone and with LY3832479 prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease – 2019 (COVID-19) in facility staff and residents in skilled nursing and assisted living facilities with a high risk of SARS-CoV-2 exposure. Participants with a high risk of SARS-CoV-2 exposure will receive LY3819253, LY3819253 and LY3832479, or placebo via an injection into a vein. Samples will be taken from the nose. Blood samples will be drawn. To speak with a study representative, call 718-210-9713.
How long will I be in the trial?
Participation could last up to 25 weeks and may include up to 19 visits.
Email

Key Requirements

Age :

18+

Sex:

All

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

All

Participants must

Participants must either live or work in a nursing home that has at least one confirmed case of COVID-19 with the last week

Participants must agree to the collection of several blood samples and swab samples from the nose

Participants must have venous access sufficient to allow intravenous infusions and blood sampling

Participant or legally authorized representative must give signed informed consent

Participants must agree to approved birth control to prevent pregnancy

Participants must NOT

Participants must not be in the hospital

Participants must not be pregnant or breastfeeding

Trial Summary

Conditions the trial is for

COVID-19 (Coronavirus)

What the trial is testing?

LY3819253, LY-CoV555, Bamlanivimab, Etsesevimab, LY3832479, LY-CoV016

Could I receive a Placebo?

yes

Enrollment Goal

5000

Trial Dates

August 2020 - June 2021

Trial Phase

3

Enter your postal code to find the nearest site

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

All

Participants must

Participants must either live or work in a nursing home that has at least one confirmed case of COVID-19 with the last week

Participants must agree to the collection of several blood samples and swab samples from the nose

Participants must have venous access sufficient to allow intravenous infusions and blood sampling

Participant or legally authorized representative must give signed informed consent

Participants must agree to approved birth control to prevent pregnancy

Participants must NOT

Participants must not be in the hospital

Participants must not be pregnant or breastfeeding

Trial Summary

Conditions the trial is for

COVID-19 (Coronavirus)

What the trial is testing?

LY3819253, LY-CoV555, Bamlanivimab, Etsesevimab, LY3832479, LY-CoV016

Could I receive a Placebo?

yes

Enrollment Goal

5000

Trial Dates

August 2020 - June 2021

Trial Phase

3

Not the right fit? Sign up to receive updates on new trials.

Trial Locations

Hide locations not currently recruiting

Enter your postal code to see sites near you

COVID-19 (Coronavirus) Resources

COVID-19 teams chat

COVID-19 Research

COVID-19 is caused by SARS-CoV-2, a novel coronavirus. Because it is a relatively new disease, scientists and physicians do not know much about it, and currently, there are not many medicines to treat it. That’s why we need clinical research—to test potential new treatments for COVID-19. Read on to see if a clinical trial may be right for you.
COVID-19

Types of Clinical Research for COVID-19

As the world works to quickly learn about COVID-19, a mix of research studies is underway. This guide explains the different types of COVID-19 studies and what researchers hope to learn from them.
COVID-19

Lilly's COVID-19 Clinical Trials are Underway

Lilly has worked quickly to launch studies of potential COVID-19 antibody treatments. Find out what makes antibodies an intriguing scientific and medical option.
Clinical Trial Participation: What to Expect

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study in people that helps to determine if and how a drug or therapy works. These can also be called clinical studies, or clinical research. Clinical research helps us answer specific questions about an investigational drug , such as: Is it effective? Is it more effective than another established treatment? Is it safe and/or what are its side effects?