Completed
A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Preventing SARS-CoV-2 Infection and COVID-19 in Nursing Home Residents and Staff (BLAZE-2)
J2X-MC-PYAD - ClinicalTrials.gov - NCT04497987
The purpose of this study is to evaluate whether LY3819253 given alone and with LY3832479 prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease – 2019 (COVID-19) in facility staff and residents in skilled nursing and assisted living facilities with a high risk of SARS-CoV-2 exposure. Participants with a high risk of SARS-CoV-2 exposure will receive LY3819253, LY3819253 and LY3832479, or placebo via an injection into a vein. Samples will be taken from the nose. Blood samples will be drawn. To speak with a study representative, call 718-210-9713.
How long will I be in the trial?
Participation could last up to 25 weeks and may include up to 19 visits.
Completed
A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Preventing SARS-CoV-2 Infection and COVID-19 in Nursing Home Residents and Staff (BLAZE-2)
J2X-MC-PYAD - ClinicalTrials.gov - NCT04497987
The purpose of this study is to evaluate whether LY3819253 given alone and with LY3832479 prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease – 2019 (COVID-19) in facility staff and residents in skilled nursing and assisted living facilities with a high risk of SARS-CoV-2 exposure. Participants with a high risk of SARS-CoV-2 exposure will receive LY3819253, LY3819253 and LY3832479, or placebo via an injection into a vein. Samples will be taken from the nose. Blood samples will be drawn. To speak with a study representative, call 718-210-9713.
How long will I be in the trial?
Participation could last up to 25 weeks and may include up to 19 visits.
Key Requirements
Age :
18+
Sex:
All
Key Requirements
Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.
Age
18+
Sex
All
Participants must
Participants must either live or work in a nursing home that has at least one confirmed case of COVID-19 with the last week
Participants must agree to the collection of several blood samples and swab samples from the nose
Participants must have venous access sufficient to allow intravenous infusions and blood sampling
Participant or legally authorized representative must give signed informed consent
Participants must agree to approved birth control to prevent pregnancy
Participants must NOT
Participants must not be in the hospital
Participants must not be pregnant or breastfeeding
Trial Summary
Conditions the trial is for
COVID-19 (Coronavirus)
What the trial is testing?
LY3819253, LY-CoV555, Bamlanivimab, Etsesevimab, LY3832479, LY-CoV016
Could I receive a Placebo?
yes
Enrollment Goal
5000
Trial Dates
August 2020 - May 2021
Trial Phase
3
Enter your postal code to find the nearest site
Key Requirements
Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.
Age
18+
Sex
All
Participants must
Participants must either live or work in a nursing home that has at least one confirmed case of COVID-19 with the last week
Participants must agree to the collection of several blood samples and swab samples from the nose
Participants must have venous access sufficient to allow intravenous infusions and blood sampling
Participant or legally authorized representative must give signed informed consent
Participants must agree to approved birth control to prevent pregnancy
Participants must NOT
Participants must not be in the hospital
Participants must not be pregnant or breastfeeding
Trial Summary
Conditions the trial is for
COVID-19 (Coronavirus)
What the trial is testing?
LY3819253, LY-CoV555, Bamlanivimab, Etsesevimab, LY3832479, LY-CoV016
Could I receive a Placebo?
yes
Enrollment Goal
5000
Trial Dates
August 2020 - May 2021
Trial Phase
3
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Trial Locations
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COVID-19 (Coronavirus) Resources
COVID-19 Research
COVID-19 is caused by SARS-CoV-2, a novel coronavirus. Because it is a relatively new disease, scientists and physicians do not know much about it, and currently, there are not many medicines to treat it. That’s why we need clinical research—to test potential new treatments for COVID-19. Read on to see if a clinical trial may be right for you.
