Recruiting

Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis (ADvocate1)

J2T-DM-KGAB - ClinicalTrials.gov - NCT04146363

The study is designed to confirm the safety and efficacy of lebrikizumab as monotherapy for treatment of moderate-to-severe atopic dermatitis.
How long will I be in the trial?
The study will last about 66 weeks and may include up to 20 visits.
Email
Recruiting

Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis (ADvocate1)

J2T-DM-KGAB - ClinicalTrials.gov - NCT04146363

The study is designed to confirm the safety and efficacy of lebrikizumab as monotherapy for treatment of moderate-to-severe atopic dermatitis.
How long will I be in the trial?
The study will last about 66 weeks and may include up to 20 visits.
Email

Key Requirements

Age :

12+

Sex:

All

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

12+

Sex

All

Participants must

Participant must be an adult (≥18 years) or adolescent (12 to <18years) and weighing ≥40kg

Participants must have atopic dermatitis that has been present for at least one year

Participants must have ≥10% body surface area (BSA) of atopic dermatitis involvement

Participants must have had an inadequate response to treatment with topical medications and must not have had treatment with the medications dupilumab, tralokinumab or lebrikizumab

Participants must NOT

Participant must not have used certain topical atopic dermatitis treatment within 1 week

Participants must not have received a vaccine within 12 weeks of starting the study

Participants must not have hepatitis

Participants must not have a history of HIV

Participants must not have a history of cancer within 5 years

Women must not be pregnant, breastfeeding or plan to become pregnant during the study

Trial Summary

Conditions the trial is for

Atopic Dermatitis (Eczema)

What the trial is testing?

Lebrikizumab

Could I receive a Placebo?

yes

Enrollment Goal

400

Trial Dates

September 2019 - May 2022

Trial Phase

3

Enter your postal code to find the nearest site

Think this trial might be a good fit for you?

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

12+

Sex

All

Participants must

Participant must be an adult (≥18 years) or adolescent (12 to <18years) and weighing ≥40kg

Participants must have atopic dermatitis that has been present for at least one year

Participants must have ≥10% body surface area (BSA) of atopic dermatitis involvement

Participants must have had an inadequate response to treatment with topical medications and must not have had treatment with the medications dupilumab, tralokinumab or lebrikizumab

Participants must NOT

Participant must not have used certain topical atopic dermatitis treatment within 1 week

Participants must not have received a vaccine within 12 weeks of starting the study

Participants must not have hepatitis

Participants must not have a history of HIV

Participants must not have a history of cancer within 5 years

Women must not be pregnant, breastfeeding or plan to become pregnant during the study

Trial Summary

Conditions the trial is for

Atopic Dermatitis (Eczema)

What the trial is testing?

Lebrikizumab

Could I receive a Placebo?

yes

Enrollment Goal

400

Trial Dates

September 2019 - May 2022

Trial Phase

3

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Trial Locations

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Atopic Dermatitis (Eczema) Resources

Clinical Trial Participation: What to Expect

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study in people that helps to determine if and how a drug or therapy works. These can also be called clinical studies, or clinical research. Clinical research helps us answer specific questions about an investigational drug , such as: Is it effective? Is it more effective than another established treatment? Is it safe and/or what are its side effects?