Active not recruiting

A Study of Abemaciclib (LY2835219) in Participants With Previously Treated KRAS Mutated Lung Cancer (JUNIPER)

I3Y-MC-JPBK - ClinicalTrials.gov - NCT02152631

The main purpose of this study is to evaluate how safe and effective the study drug known as abemaciclib is in participants with lung cancer.
How long will I be in the trial?
This trial could take up to 7 months, depending on how you and your tumor respond
Email
Active not recruiting

A Study of Abemaciclib (LY2835219) in Participants With Previously Treated KRAS Mutated Lung Cancer (JUNIPER)

I3Y-MC-JPBK - ClinicalTrials.gov - NCT02152631

The main purpose of this study is to evaluate how safe and effective the study drug known as abemaciclib is in participants with lung cancer.
How long will I be in the trial?
This trial could take up to 7 months, depending on how you and your tumor respond
Email

Key Requirements

Age :

18+

Sex:

All

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

All

Participants must

Participant must have confirmed diagnosis of stage IV non-small cell lung cancer (NSCLC)

Participant must have a tumor with a KRAS mutation (this will be checked for at screening)

Participant must have received prior chemotherapy

Participants must NOT

Participant must not have an active infection with HIV, Hepatitis B or C, or a history of cardiac arrest

Female participant must not be pregnant or lactating

Trial Summary

Conditions the trial is for

Non-small Cell Lung Cancer, Solid Tumor

What the trial is testing?

Abemaciclib, Erlotinib

Could I receive a Placebo?

no

Enrollment Goal

450

Trial Dates

October 2014 - September 2021

Trial Phase

3

Enter your postal code to find the nearest site

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

All

Participants must

Participant must have confirmed diagnosis of stage IV non-small cell lung cancer (NSCLC)

Participant must have a tumor with a KRAS mutation (this will be checked for at screening)

Participant must have received prior chemotherapy

Participants must NOT

Participant must not have an active infection with HIV, Hepatitis B or C, or a history of cardiac arrest

Female participant must not be pregnant or lactating

Trial Summary

Conditions the trial is for

Non-small Cell Lung Cancer, Solid Tumor

What the trial is testing?

Abemaciclib, Erlotinib

Could I receive a Placebo?

no

Enrollment Goal

450

Trial Dates

October 2014 - September 2021

Trial Phase

3

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Trial Locations

Hide locations not currently recruiting

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Resources

Clinical Trial Participation: What to Expect

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study in people that helps to determine if and how a drug or therapy works. These can also be called clinical studies, or clinical research. Clinical research helps us answer specific questions about an investigational drug , such as: Is it effective? Is it more effective than another established treatment? Is it safe and/or what are its side effects?