Completed Enrollment

A Study of Abemaciclib (LY2835219) in Participants With Previously Treated KRAS Mutated Lung Cancer (JUNIPER)

The main purpose of this study is to evaluate how safe and effective the study drug known as abemaciclib is in participants with lung cancer.

Trial Summary

Age Range
≥18 years
Conditions the trial is for
Non-Small Cell Lung Cancer
What the trial is testing?
Abemaciclib, Erlotinib
Could I receive a Placebo?
No
Enrollment Goal
453
Trial Dates
Oct 3, 2014 - Dec 2024
How long will I be in the trial?
This trial could take up to 7 months, depending on how you and your tumor respond.
Trial Phase
III

Key Requirements

Clinical trials have inclusion and exclusion requirements to determine which individuals qualify for participation. Listed below are key requirements for this clinical trial, but there may be additional requirements to qualify.

Participants Must:

  • Participant must have confirmed diagnosis of stage IV non-small cell lung cancer (NSCLC)

  • Participant must have a tumor with a KRAS mutation (this will be checked for at screening)

  • Participant must have received prior chemotherapy

Participants Must Not:

  • Participant must not have an active infection with HIV, Hepatitis B or C, or a history of cardiac arrest

  • Female participant must not be pregnant or lactating

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Clinical Trial Participation: What to Expect

A clinical trial is a scientific study. It helps us learn if a new medicine or treatment works and how it works. Clinical trials can also be called clinical research studies. Learn more about clinical research studies and what to expect when taking part in a clinical trial.