Completed

A Study of Enzalutamide and LY3023414 in Men with Prostate Cancer

I6A-MC-CBBD - ClinicalTrials.gov - NCT02407054

The main purpose of this study is to evaluate the safety and effectiveness of the study drug known as LY3023414 in combination with enzalutamide in men with prostate cancer.
How long will I be in the trial?
Your participation could last up to 56 days or longer if you are tolerating the study drug and your study doctor thinks your condition is stable or improving.
Email
Completed

A Study of Enzalutamide and LY3023414 in Men with Prostate Cancer

I6A-MC-CBBD - ClinicalTrials.gov - NCT02407054

The main purpose of this study is to evaluate the safety and effectiveness of the study drug known as LY3023414 in combination with enzalutamide in men with prostate cancer.
How long will I be in the trial?
Your participation could last up to 56 days or longer if you are tolerating the study drug and your study doctor thinks your condition is stable or improving.
Email

Key Requirements

Age :

18+

Sex:

Male

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

Male

Participants must

Participant must have diagnosis of prostate cancer

Participant must have metastatic disease

Participant must have completed and failed prior abiraterone treatment

Participant must be surgically or medically castrated

Participant must be able to swallow the study drug (pills) whole

Participants must NOT

Participant must not have had prior treatment with chemotherapy or enzalutamide

Participant must not have known brain metastases or uncontrolled hypertension

Participant must not have insulin-dependent diabetes mellitus, however participants with type 2 diabetes mellitus may be eligible

Participant must not have an active, known fungal, bacterial, and/or known viral infection

Trial Summary

Conditions the trial is for

Prostate Cancer

What the trial is testing?

LY3023414 + Enzalutamide, Placebo + Enzalutamide

Could I receive a Placebo?

yes

Enrollment Goal

144

Trial Dates

April 2015 - April 2020

Trial Phase

2

Enter your postal code to find the nearest site

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

Male

Participants must

Participant must have diagnosis of prostate cancer

Participant must have metastatic disease

Participant must have completed and failed prior abiraterone treatment

Participant must be surgically or medically castrated

Participant must be able to swallow the study drug (pills) whole

Participants must NOT

Participant must not have had prior treatment with chemotherapy or enzalutamide

Participant must not have known brain metastases or uncontrolled hypertension

Participant must not have insulin-dependent diabetes mellitus, however participants with type 2 diabetes mellitus may be eligible

Participant must not have an active, known fungal, bacterial, and/or known viral infection

Trial Summary

Conditions the trial is for

Prostate Cancer

What the trial is testing?

LY3023414 + Enzalutamide, Placebo + Enzalutamide

Could I receive a Placebo?

yes

Enrollment Goal

144

Trial Dates

April 2015 - April 2020

Trial Phase

2

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Trial Locations

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Prostate Cancer Resources

Clinical Trial Participation: What to Expect

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study in people that helps to determine if and how a drug or therapy works. These can also be called clinical studies, or clinical research. Clinical research helps us answer specific questions about an investigational drug , such as: Is it effective? Is it more effective than another established treatment? Is it safe and/or what are its side effects?