Active not recruiting

A Study of Ramucirumab (LY3009806) in Children With Refractory Solid Tumors

I4T-MC-JVDA - ClinicalTrials.gov - NCT02564198

The main purpose of this study is to evaluate the safety of the study drug known as ramucirumab in children with recurrent or refractory solid tumors including central nervous system (CNS) tumors.
How long will I be in the trial?
Your participation could last up to 12 months depending on how you and your tumor respond.
Email
Active not recruiting

A Study of Ramucirumab (LY3009806) in Children With Refractory Solid Tumors

I4T-MC-JVDA - ClinicalTrials.gov - NCT02564198

The main purpose of this study is to evaluate the safety of the study drug known as ramucirumab in children with recurrent or refractory solid tumors including central nervous system (CNS) tumors.
How long will I be in the trial?
Your participation could last up to 12 months depending on how you and your tumor respond.
Email

Key Requirements

Age (months):

12-21

Sex:

All

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age (months)

12-21

Sex

All

Participants must

For Part A of the trial, participant must have recurrent or refractory non-central nervous system (CNS) solid tumors

For Part B of the trial, participant must have recurrent or refractory central nervous system (CNS) tumors

Participants must NOT

Participant must not have other treatment options

Participant must not have active or recent history of serious bleeding events

Participant must not have active or recent history of gastrointestinal perforations, ulcers, fistulas or abscesses

Participant must not have active or recent history of dangerously high blood pressure or headache, convulsions or coma related to high blood pressure

Participant must not have an active, non-healing wound or bone fracture

Participant must not have a history of organ transplant

Trial Summary

Conditions the trial is for

Pediatric Solid Tumors, Pediatric Central Nervous System (CNS) Cancer

What the trial is testing?

Ramucirumab

Could I receive a Placebo?

no

Enrollment Goal

36

Trial Dates

December 2015 - March 2020

Trial Phase

1

Enter your postal code to find the nearest site

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age (months)

12-21

Sex

All

Participants must

For Part A of the trial, participant must have recurrent or refractory non-central nervous system (CNS) solid tumors

For Part B of the trial, participant must have recurrent or refractory central nervous system (CNS) tumors

Participants must NOT

Participant must not have other treatment options

Participant must not have active or recent history of serious bleeding events

Participant must not have active or recent history of gastrointestinal perforations, ulcers, fistulas or abscesses

Participant must not have active or recent history of dangerously high blood pressure or headache, convulsions or coma related to high blood pressure

Participant must not have an active, non-healing wound or bone fracture

Participant must not have a history of organ transplant

Trial Summary

Conditions the trial is for

Pediatric Solid Tumors, Pediatric Central Nervous System (CNS) Cancer

What the trial is testing?

Ramucirumab

Could I receive a Placebo?

no

Enrollment Goal

36

Trial Dates

December 2015 - March 2020

Trial Phase

1

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Trial Locations

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Resources

Clinical Trial Participation: What to Expect

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study in people that helps to determine if and how a drug or therapy works. These can also be called clinical studies, or clinical research. Clinical research helps us answer specific questions about an investigational drug , such as: Is it effective? Is it more effective than another established treatment? Is it safe and/or what are its side effects?