Active not recruiting

A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer

I3Y-CR-JPBQ - ClinicalTrials.gov - NCT02763566

The main purpose of this study is to evaluate the efficacy of the study drug Abemaciclib (LY2835219) and other therapies in postmenopausal women with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) locoregionally recurrent or metastatic breast cancer
How long will I be in the trial?
Your participation could last up to 18 months depending on how you and your tumor respond.
Email
Active not recruiting

A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer

I3Y-CR-JPBQ - ClinicalTrials.gov - NCT02763566

The main purpose of this study is to evaluate the efficacy of the study drug Abemaciclib (LY2835219) and other therapies in postmenopausal women with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) locoregionally recurrent or metastatic breast cancer
How long will I be in the trial?
Your participation could last up to 18 months depending on how you and your tumor respond.
Email

Key Requirements

Age :

18+

Sex:

Female

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

Female

Participants must

Participant must have a diagnosis of HR+, HER2- breast cancer

Participant must be able to swallow capsules

Participants must NOT

Participant must not be currently enrolled in a clinical trial involving an investigational product (IP) or non-approved use of a drug or device (other than the IP/device used in this study)

Participant must not have inflammatory breast cancer

Participant must not have received recent (within 28 days prior to randomization) live attenuated vaccines such as yellow fever vaccine

Participant must not have a history of any other cancer (except nonmelanoma skin cancer or carcinoma in-situ of the cervix), unless in complete remission with no therapy for a minimum of 3 years

Participant must not have received an autologous or allogeneic stem-cell transplant

Trial Summary

Conditions the trial is for

Breast Cancer, Solid Tumor

What the trial is testing?

Abemaciclib, Anastrozole, Letrozole, Placebo, Fulvestrant

Could I receive a Placebo?

yes

Enrollment Goal

450

Trial Dates

December 2016 - July 2021

Trial Phase

3

Enter your postal code to find the nearest site

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

Female

Participants must

Participant must have a diagnosis of HR+, HER2- breast cancer

Participant must be able to swallow capsules

Participants must NOT

Participant must not be currently enrolled in a clinical trial involving an investigational product (IP) or non-approved use of a drug or device (other than the IP/device used in this study)

Participant must not have inflammatory breast cancer

Participant must not have received recent (within 28 days prior to randomization) live attenuated vaccines such as yellow fever vaccine

Participant must not have a history of any other cancer (except nonmelanoma skin cancer or carcinoma in-situ of the cervix), unless in complete remission with no therapy for a minimum of 3 years

Participant must not have received an autologous or allogeneic stem-cell transplant

Trial Summary

Conditions the trial is for

Breast Cancer, Solid Tumor

What the trial is testing?

Abemaciclib, Anastrozole, Letrozole, Placebo, Fulvestrant

Could I receive a Placebo?

yes

Enrollment Goal

450

Trial Dates

December 2016 - July 2021

Trial Phase

3

Not the right fit? Sign up to receive updates on new trials.

Trial Locations

Hide locations not currently recruiting

Enter your postal code to see sites near you

Resources

Clinical Trial Participation: What to Expect

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study in people that helps to determine if and how a drug or therapy works. These can also be called clinical studies, or clinical research. Clinical research helps us answer specific questions about an investigational drug , such as: Is it effective? Is it more effective than another established treatment? Is it safe and/or what are its side effects?