A Study of LY3361237 in Participants With Psoriasis

I9S-MC-BTAC -

The main purpose of this study is to learn more about the safety and tolerability of LY3361237 and any side effects that might be associated with it when given to participants with psoriasis. LY3361237 will be administered by injections just under the skin.

Trial Summary

Age Range
18 - 70 years
Conditions the trial is for
Psoriasis
What the trial is testing?
LY3361237
Could I receive a Placebo?
Yes
Enrollment Goal
21
Trial Dates
Jul 27, 2021 - Nov 29, 2022
How long will I be in the trial?
Your participation could last about 41 weeks and may include up to 15 visits to the study center.
Trial Phase
I

Key Requirements

Clinical trials have inclusion and exclusion requirements to determine which individuals qualify for participation. Listed below are key requirements for this clinical trial, but there may be additional requirements to qualify.

Participants Must:

  • Participants must have chronic plaque psoriasis for at least 6 months

  • Participants must be willing and able to have skin biopsies (small samples of skin removed for testing)

  • Participants must have a body mass index 18-40 kg/m2

  • Female participants must agree to use birth control during the study

Participants Must Not:

  • Participants must not have had certain types of infection within the last six months

  • Participants must not have a clinically significant active infection, or recent acute active infection within the last 30 days

  • Participants must not have other serious or unstable illnesses

  • Participants must not have a history of organ or bone marrow transplant

  • Participants must not have received any live vaccine within the last 4 weeks prior to screening

  • Participants must not have received certain oral or injectable medications for psoriasis (systemic nonbiologic psoriasis therapy) within 4 weeks prior to study day 1

  • Participants must not have received topical psoriasis treatment within 14 days prior to study day 1

  • Participants must not have excessive skin exposure or use tanning booths for at least 4 weeks prior to study day 1

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