Enrolling

A Study of Baricitinib (LY3009104) in Participants From 1 Year to Less Than 18 Years Old With sJIA

I4V-MC-JAHU -

The reason for this study is to see if the study drug baricitinib is safe and effective in participants from 1 year to less than 18 years old with systemic juvenile idiopathic arthritis (sJIA).

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See if You May Qualify

Answer a few questions to see if you meet key criteria for this study.

Trial Summary

Age Range
1 year - 17 years
Conditions the trial is for
Systemic Juvenile Idiopathic Arthritis
What the trial is testing?
Baricitinib
Could I receive a Placebo?
Yes
Enrollment Goal
103
Trial Dates
Feb 12, 2020 - Oct 2025
How long will I be in the trial?
The study will last about 164 weeks and may include up to 30 visits.
Trial Phase
III

Key Requirements

Clinical trials have inclusion and exclusion requirements to determine which individuals qualify for participation. Listed below are key requirements for this clinical trial, but there may be additional requirements to qualify.

Participants Must:

  • Participants must have systemic Juvenile Idiopathic Arthritis (sJIA) with onset before the age of 16 years

  • Participants must have arthritis in a joint and fever lasting 2 weeks, with daily fever for 3 days, and at least 1 of the following: Evanescent erythematous rash, generalized lymph node enlargement, enlarged liver/spleen, serositis

  • Participants must have at least 2 active joints

Participants Must Not:

  • Participants must not have polyarticular JIA, extended oligoarticular JIA, enthesitis related JIA or juvenile psoriatic arthritis

  • Participants must not have persistent oligoarticular arthritis

  • Participants must not have any autoimmune inflammatory condition other than JIA

  • Participants must not have active anterior uveitis

  • Participants must not have active fibromyalgia or other chronic pain conditions

  • Participants must not have an infection

  • Participants must not have hepatitis B or tuberculosis (TB)

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