Active not recruiting
A Study of Tirzepatide (LY3298176) Versus Semaglutide Once Weekly as Add-on Therapy to Metformin in Participants With Type 2 Diabetes
I8F-MC-GPGL - ClinicalTrials.gov - NCT03987919
The reason for this study is to compare the effect of the study drug tirzepatide to semaglutide on blood sugar levels in participants with type 2 diabetes.
How long will I be in the trial?
The study will last approximately 47 weeks and may include about 12 visits.
Active not recruiting
A Study of Tirzepatide (LY3298176) Versus Semaglutide Once Weekly as Add-on Therapy to Metformin in Participants With Type 2 Diabetes
I8F-MC-GPGL - ClinicalTrials.gov - NCT03987919
The reason for this study is to compare the effect of the study drug tirzepatide to semaglutide on blood sugar levels in participants with type 2 diabetes.
How long will I be in the trial?
The study will last approximately 47 weeks and may include about 12 visits.
Key Requirements
Age :
18+
Sex:
All
Key Requirements
Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.
Age
18+
Sex
All
Participants must
Participant must have type 2 diabetes mellitus (T2DM)
Participant must have HbA1c between >7.0% and <10.5%
Participant must be on stable treatment dose of metformin
Participant must be of stable weight
Participants must NOT
Participant must not have type 1 diabetes
Participant must not have pancreatitis
Participant must not have disorders with slowed emptying of the stomach contents, or have had any stomach surgeries for the purpose of weight loss
Participant must not have a personal or family history of medullary thyroid carcinoma or personal history of multiple endocrine neoplasia syndrome type 2
Participant must not have had a heart attack stroke, or hospitalization for congestive heart failure in the past 2 months
Participant must not have been taking weight loss drugs including over-the-counter medications during the last 3 months
Trial Summary
Conditions the trial is for
Adult Type 2 Diabetes
What the trial is testing?
Tirzepatide, Semaglutide
Could I receive a Placebo?
no
Enrollment Goal
1872
Trial Dates
July 2019 - February 2021
Trial Phase
3
Enter your postal code to find the nearest site
Key Requirements
Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.
Age
18+
Sex
All
Participants must
Participant must have type 2 diabetes mellitus (T2DM)
Participant must have HbA1c between >7.0% and <10.5%
Participant must be on stable treatment dose of metformin
Participant must be of stable weight
Participants must NOT
Participant must not have type 1 diabetes
Participant must not have pancreatitis
Participant must not have disorders with slowed emptying of the stomach contents, or have had any stomach surgeries for the purpose of weight loss
Participant must not have a personal or family history of medullary thyroid carcinoma or personal history of multiple endocrine neoplasia syndrome type 2
Participant must not have had a heart attack stroke, or hospitalization for congestive heart failure in the past 2 months
Participant must not have been taking weight loss drugs including over-the-counter medications during the last 3 months
Trial Summary
Conditions the trial is for
Adult Type 2 Diabetes
What the trial is testing?
Tirzepatide, Semaglutide
Could I receive a Placebo?
no
Enrollment Goal
1872
Trial Dates
July 2019 - February 2021
Trial Phase
3
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Trial Locations
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