Completed

A Study of LY3127804 with Ramucirumab in Participants with Advanced Solid Tumors

I7W-MC-JQBA - ClinicalTrials.gov - NCT02597036

The main purpose of this study is to evaluate the safety of the study drug known as LY3127804 given as monotherapy and in combination with Ramucirumab for participants with advanced or metastatic solid tumors. The study will also include a safety exploration for the combination of LY3127804 plus ramucirumab and paclitaxel.
How long will I be in the trial?
Your participation could last up to 2 months depending on how you and your tumor respond.
Email
Completed

A Study of LY3127804 with Ramucirumab in Participants with Advanced Solid Tumors

I7W-MC-JQBA - ClinicalTrials.gov - NCT02597036

The main purpose of this study is to evaluate the safety of the study drug known as LY3127804 given as monotherapy and in combination with Ramucirumab for participants with advanced or metastatic solid tumors. The study will also include a safety exploration for the combination of LY3127804 plus ramucirumab and paclitaxel.
How long will I be in the trial?
Your participation could last up to 2 months depending on how you and your tumor respond.
Email

Key Requirements

Age :

18+

Sex:

All

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

All

Participants must

Participant must have a diagnosis of cancer that is advanced and/or metastatic

Participant must have adequate organ function

Participants must NOT

Participant must not have any current blood cancers

Participant must not have an active fungal, bacterial, and/or known viral infection

Participant must not have a history or dangerously high blood pressure, headache, convulsions, or coma related to high blood pressure or poorly controlled hypertension despite standard medical management

Participant must not be pregnant or breastfeeding

Trial Summary

Conditions the trial is for

Solid Tumor

What the trial is testing?

LY3127804, Ramucirumab, Paclitaxel

Could I receive a Placebo?

no

Enrollment Goal

105

Trial Dates

November 2015 - May 2020

Trial Phase

1

Enter your postal code to find the nearest site

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

All

Participants must

Participant must have a diagnosis of cancer that is advanced and/or metastatic

Participant must have adequate organ function

Participants must NOT

Participant must not have any current blood cancers

Participant must not have an active fungal, bacterial, and/or known viral infection

Participant must not have a history or dangerously high blood pressure, headache, convulsions, or coma related to high blood pressure or poorly controlled hypertension despite standard medical management

Participant must not be pregnant or breastfeeding

Trial Summary

Conditions the trial is for

Solid Tumor

What the trial is testing?

LY3127804, Ramucirumab, Paclitaxel

Could I receive a Placebo?

no

Enrollment Goal

105

Trial Dates

November 2015 - May 2020

Trial Phase

1

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Trial Locations

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Solid Tumor Resources

Clinical Trial Participation: What to Expect

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study in people that helps to determine if and how a drug or therapy works. These can also be called clinical studies, or clinical research. Clinical research helps us answer specific questions about an investigational drug , such as: Is it effective? Is it more effective than another established treatment? Is it safe and/or what are its side effects?