Active not recruiting

A Study of LY3303560 in Participants With Early Symptomatic Alzheimer's Disease

I8G-MC-LMDC - ClinicalTrials.gov - NCT03518073

The purpose of this study is to evaluate the safety and efficacy of a study drug that targets an abnormal protein in the brain found in people with Alzheimer's Disease (AD).
How long will I be in the trial?
The study will last about 128 weeks and may include up to 27 visits.
Email
Active not recruiting

A Study of LY3303560 in Participants With Early Symptomatic Alzheimer's Disease

I8G-MC-LMDC - ClinicalTrials.gov - NCT03518073

The purpose of this study is to evaluate the safety and efficacy of a study drug that targets an abnormal protein in the brain found in people with Alzheimer's Disease (AD).
How long will I be in the trial?
The study will last about 128 weeks and may include up to 27 visits.
Email

Key Requirements

Age :

60-85

Sex:

All

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

60-85

Sex

All

Participants must

Participants must have gradual and progressive change in memory function for >6 months

Participants must have a family member or close friend who is with participant at least 10 hours per week and can attend study appointments

Participants must NOT

Participants must not have significant neurological disease affecting the nervous system, other than AD, that affects cognition or may affect completion of the study

Participants must not have serious or unstable illness that could interfere with the analysis of the study or have a life expectancy <24 months

Participants must not have history of cancer within the last 5 years with the exception of certain types of skin, cervical, prostate, and other cancers that are not likely to recur or spread

Participants must not have serious risk for suicide

Participants must not have history of drug or alcohol use disorder within the last 2 years

Participants must not have multiple severe drug allergies

Participants must not have HIV, Hepatitis B or Hepatitis C

Trial Summary

Conditions the trial is for

Early Symptoms of Alzheimer's Disease

What the trial is testing?

LY3303560, Placebo

Could I receive a Placebo?

yes

Enrollment Goal

285

Trial Dates

April 2018 - October 2021

Trial Phase

2

Enter your postal code to find the nearest site

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

60-85

Sex

All

Participants must

Participants must have gradual and progressive change in memory function for >6 months

Participants must have a family member or close friend who is with participant at least 10 hours per week and can attend study appointments

Participants must NOT

Participants must not have significant neurological disease affecting the nervous system, other than AD, that affects cognition or may affect completion of the study

Participants must not have serious or unstable illness that could interfere with the analysis of the study or have a life expectancy <24 months

Participants must not have history of cancer within the last 5 years with the exception of certain types of skin, cervical, prostate, and other cancers that are not likely to recur or spread

Participants must not have serious risk for suicide

Participants must not have history of drug or alcohol use disorder within the last 2 years

Participants must not have multiple severe drug allergies

Participants must not have HIV, Hepatitis B or Hepatitis C

Trial Summary

Conditions the trial is for

Early Symptoms of Alzheimer's Disease

What the trial is testing?

LY3303560, Placebo

Could I receive a Placebo?

yes

Enrollment Goal

285

Trial Dates

April 2018 - October 2021

Trial Phase

2

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Trial Locations

Hide locations not currently recruiting

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Early Symptoms of Alzheimer's Disease Resources

Memory, Alzheimer’s Disease, and Research Studies

Memory, Alzheimer’s Disease, and Research Studies

With the help of research study participants, we are learning about aging, memory, and potential new approaches to fighting Alzheimer’s disease.
Clinical Trial Participation: What to Expect

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study in people that helps to determine if and how a drug or therapy works. These can also be called clinical studies, or clinical research. Clinical research helps us answer specific questions about an investigational drug , such as: Is it effective? Is it more effective than another established treatment? Is it safe and/or what are its side effects?