Completed

A Study of Abemaciclib (LY2835219) in Participants With Stage IV Squamous Non-small Cell Lung Cancer

I3Y-MC-JPBX - ClinicalTrials.gov - NCT02450539

The main purpose of this study is to evaluate the effectiveness of the study drug known as abemaciclib versus docetaxel in participants with stage IV squamous non-small cell lung cancer (NSCLC) previously treated with platinum-based chemotherapy.
How long will I be in the trial?
You can participate in this study for as long as your study doctor determines that you are benefiting from the study treatment
Email
Completed

A Study of Abemaciclib (LY2835219) in Participants With Stage IV Squamous Non-small Cell Lung Cancer

I3Y-MC-JPBX - ClinicalTrials.gov - NCT02450539

The main purpose of this study is to evaluate the effectiveness of the study drug known as abemaciclib versus docetaxel in participants with stage IV squamous non-small cell lung cancer (NSCLC) previously treated with platinum-based chemotherapy.
How long will I be in the trial?
You can participate in this study for as long as your study doctor determines that you are benefiting from the study treatment
Email

Key Requirements

Age :

18+

Sex:

All

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

All

Participants must

Participant must have a confirmed diagnosis of stage IV Squamous NSCLC

Participant must have progressed during or after platinum-based chemotherapy

Participant must be fully active or if restricted in physically strenuous activity should be able to walk and carry out light work, e.g., light house work, office work

Participant must agree to use a reliable medically approved method of birth control

Participants must NOT

Participant must not have received prior treatment with docetaxel

Participant must not have received prior treatment with any cyclin dependent kinase (CDK) 4 and 6 inhibitor or participated in a clinical trial with a CDK 4 and 6 inhibitor where the treatment administered is not known

Participant must not be currently receiving treatment in a clinical trial involving an investigational product or non-approved use of a drug or device

Trial Summary

Conditions the trial is for

Non-small Cell Lung Cancer

What the trial is testing?

Abemaciclib (LY2835219), Docetaxel

Could I receive a Placebo?

no

Enrollment Goal

150

Trial Dates

August 2015 - July 2020

Trial Phase

2

Enter your postal code to find the nearest site

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

All

Participants must

Participant must have a confirmed diagnosis of stage IV Squamous NSCLC

Participant must have progressed during or after platinum-based chemotherapy

Participant must be fully active or if restricted in physically strenuous activity should be able to walk and carry out light work, e.g., light house work, office work

Participant must agree to use a reliable medically approved method of birth control

Participants must NOT

Participant must not have received prior treatment with docetaxel

Participant must not have received prior treatment with any cyclin dependent kinase (CDK) 4 and 6 inhibitor or participated in a clinical trial with a CDK 4 and 6 inhibitor where the treatment administered is not known

Participant must not be currently receiving treatment in a clinical trial involving an investigational product or non-approved use of a drug or device

Trial Summary

Conditions the trial is for

Non-small Cell Lung Cancer

What the trial is testing?

Abemaciclib (LY2835219), Docetaxel

Could I receive a Placebo?

no

Enrollment Goal

150

Trial Dates

August 2015 - July 2020

Trial Phase

2

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Trial Locations

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Non-small Cell Lung Cancer Resources

Clinical Trial Participation: What to Expect

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study in people that helps to determine if and how a drug or therapy works. These can also be called clinical studies, or clinical research. Clinical research helps us answer specific questions about an investigational drug , such as: Is it effective? Is it more effective than another established treatment? Is it safe and/or what are its side effects?