Recruiting

Chronic Pain Master Protocol (CPMP): A Study of LY3556050 in Participants With Osteoarthritis

H0P-MC-OA03 - ClinicalTrials.gov - NCT04627038

This study is being done to test the safety and efficacy of LY3556050 for the treatment of osteoarthritis pain.
How long will I be in the trial?
The study will last about 8 weeks and may include up to 5 visits.
Email
Recruiting

Chronic Pain Master Protocol (CPMP): A Study of LY3556050 in Participants With Osteoarthritis

H0P-MC-OA03 - ClinicalTrials.gov - NCT04627038

This study is being done to test the safety and efficacy of LY3556050 for the treatment of osteoarthritis pain.
How long will I be in the trial?
The study will last about 8 weeks and may include up to 5 visits.
Email

Key Requirements

Age :

40+

Sex:

All

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

40+

Sex

All

Participants must

Participants must have a body mass index <40 kilograms per meter squared (kg/m2)

Participants must be willing to maintain any non-drug pain relieving therapies (for example, physical therapy) and not start any new non-drug pain-relieving therapies during the study

Participants must be willing to stop all pain medications for osteoarthritis, except for rescue medication allowed in the study

Participants must have index knee pain for at least 12 weeks

Participants must NOT

Participants must not have had a procedure within the past 6 months intended to produce permanent sensory loss in the target area of interest (for example, ablation techniques)

Participants must not have surgery planned during the study for any reason

Participants must not have had cancer within 2 years, except for certain types of skin cancer (cutaneous basal cell or squamous cell carcinoma) surgically removed

Participants must not have an intolerance to acetaminophen or paracetamol

Participants must not have an unstable index joint (such as a torn anterior cruciate ligament), surgical hardware or have had a surgical procedure or therapeutic injection in the affected knee within 3 months

Trial Summary

Conditions the trial is for

Osteoarthritis

What the trial is testing?

LY3556050

Could I receive a Placebo?

yes

Enrollment Goal

200

Trial Dates

November 2020 - July 2021

Trial Phase

2

Enter your postal code to find the nearest site

Think this trial might be a good fit for you?

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

40+

Sex

All

Participants must

Participants must have a body mass index <40 kilograms per meter squared (kg/m2)

Participants must be willing to maintain any non-drug pain relieving therapies (for example, physical therapy) and not start any new non-drug pain-relieving therapies during the study

Participants must be willing to stop all pain medications for osteoarthritis, except for rescue medication allowed in the study

Participants must have index knee pain for at least 12 weeks

Participants must NOT

Participants must not have had a procedure within the past 6 months intended to produce permanent sensory loss in the target area of interest (for example, ablation techniques)

Participants must not have surgery planned during the study for any reason

Participants must not have had cancer within 2 years, except for certain types of skin cancer (cutaneous basal cell or squamous cell carcinoma) surgically removed

Participants must not have an intolerance to acetaminophen or paracetamol

Participants must not have an unstable index joint (such as a torn anterior cruciate ligament), surgical hardware or have had a surgical procedure or therapeutic injection in the affected knee within 3 months

Trial Summary

Conditions the trial is for

Osteoarthritis

What the trial is testing?

LY3556050

Could I receive a Placebo?

yes

Enrollment Goal

200

Trial Dates

November 2020 - July 2021

Trial Phase

2

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Trial Locations

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Osteoarthritis Resources

Clinical Trial Participation: What to Expect

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study in people that helps to determine if and how a drug or therapy works. These can also be called clinical studies, or clinical research. Clinical research helps us answer specific questions about an investigational drug , such as: Is it effective? Is it more effective than another established treatment? Is it safe and/or what are its side effects?