Enrolling

A Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 3)

I6T-MC-AMAP -

This study is designed to evaluate the long-term efficacy and safety of mirikizumab in participants with moderately to severely active ulcerative colitis (UC).

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See if You May Qualify

Answer a few questions to see if you meet key criteria for this study.

Trial Summary

Age Range
18 - 80 years
Conditions the trial is for
Ulcerative Colitis
What the trial is testing?
Mirikizumab
Could I receive a Placebo?
No
Enrollment Goal
1063
Trial Dates
Jul 18, 2018 - Dec 2027
How long will I be in the trial?
The study will last about 176 weeks and may include up to 43 visits.
Trial Phase
III

Key Requirements

Clinical trials have inclusion and exclusion requirements to determine which individuals qualify for participation. Listed below are key requirements for this clinical trial, but there may be additional requirements to qualify.

Participants Must:

  • Participants must have completed studies AMAC (NCT02589665) or AMBG (NCT03524092), received study drug, and did not stop study drug early

  • Female participants must agree to contraception requirements

Participants Must Not:

  • Participants must not have developed a new condition, including cancer, in the originator study

  • Participants must not have any important infections including, but not limited to, hepatitis B, hepatitis C, HIV/AIDS, and active tuberculosis (TB) during either originator study

  • Participants must not have received surgery for UC in the originator study and must not be likely to require surgery for treatment of UC during this study

  • Participants must not have developed growths, known as polyps, that develop on the lining of the large intestine during the originator study that have not been removed prior to the start of this study

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