Completed
A Study of Baricitinib (LY3009104) in Participants With COVID-19 (COV-BARRIER)
I4V-MC-KHAA - ClinicalTrials.gov - NCT04421027
The reason for this study is to see if the study drug baricitinib is effective in hospitalized participants with COVID-19.
How long will I be in the trial?
The study will last about 6 weeks and may include up to 7 visits as well as daily assessments.
Completed
A Study of Baricitinib (LY3009104) in Participants With COVID-19 (COV-BARRIER)
I4V-MC-KHAA - ClinicalTrials.gov - NCT04421027
The reason for this study is to see if the study drug baricitinib is effective in hospitalized participants with COVID-19.
How long will I be in the trial?
The study will last about 6 weeks and may include up to 7 visits as well as daily assessments.
Key Requirements
Age :
18+
Sex:
All
Key Requirements
Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.
Age
18+
Sex
All
Participants must
Be hospitalized with coronavirus (SARS-COV-2)
Need oxygen therapy when they enter the study and when assigned to treatment
Participants must NOT
Have ever received convalescent plasma or intravenous immunoglobulin [IVIg]) for COVID-19
Have received greater than 20 milligrams per day of oral corticosteroids for more than 14 days before study start
Have received antibodies that block the COVID-19 virus
Have active tuberculosis (TB)
Have an active infection (besides COVID-19)
Require a ventilator at study entry
Have cancer
Have a history of more than one blood clot or a blood clot within 12 weeks before entering study
Be pregnant or breastfeeding
Trial Summary
Conditions the trial is for
COVID-19 (Coronavirus)
What the trial is testing?
Baricitinib
Could I receive a Placebo?
yes
Enrollment Goal
1400
Trial Dates
June 2020 - June 2021
Trial Phase
3
Enter your postal code to find the nearest site
Key Requirements
Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.
Age
18+
Sex
All
Participants must
Be hospitalized with coronavirus (SARS-COV-2)
Need oxygen therapy when they enter the study and when assigned to treatment
Participants must NOT
Have ever received convalescent plasma or intravenous immunoglobulin [IVIg]) for COVID-19
Have received greater than 20 milligrams per day of oral corticosteroids for more than 14 days before study start
Have received antibodies that block the COVID-19 virus
Have active tuberculosis (TB)
Have an active infection (besides COVID-19)
Require a ventilator at study entry
Have cancer
Have a history of more than one blood clot or a blood clot within 12 weeks before entering study
Be pregnant or breastfeeding
Trial Summary
Conditions the trial is for
COVID-19 (Coronavirus)
What the trial is testing?
Baricitinib
Could I receive a Placebo?
yes
Enrollment Goal
1400
Trial Dates
June 2020 - June 2021
Trial Phase
3
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Trial Locations
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COVID-19 (Coronavirus) Resources
COVID-19 Research
COVID-19 is caused by SARS-CoV-2, a novel coronavirus. Because it is a relatively new disease, scientists and physicians do not know much about it, and currently, there are not many medicines to treat it. That’s why we need clinical research—to test potential new treatments for COVID-19. Read on to see if a clinical trial may be right for you.
