Completed

A Study of Baricitinib (LY3009104) in Participants With COVID-19 (COV-BARRIER)

I4V-MC-KHAA - ClinicalTrials.gov - NCT04421027

The reason for this study is to see if the study drug baricitinib is effective in hospitalized participants with COVID-19.
How long will I be in the trial?
The study will last about 6 weeks and may include up to 7 visits as well as daily assessments.
Email
Completed

A Study of Baricitinib (LY3009104) in Participants With COVID-19 (COV-BARRIER)

I4V-MC-KHAA - ClinicalTrials.gov - NCT04421027

The reason for this study is to see if the study drug baricitinib is effective in hospitalized participants with COVID-19.
How long will I be in the trial?
The study will last about 6 weeks and may include up to 7 visits as well as daily assessments.
Email

Key Requirements

Age :

18+

Sex:

All

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

All

Participants must

Be hospitalized with coronavirus (SARS-COV-2)

Need oxygen therapy when they enter the study and when assigned to treatment

Participants must NOT

Have ever received convalescent plasma or intravenous immunoglobulin [IVIg]) for COVID-19

Have received greater than 20 milligrams per day of oral corticosteroids for more than 14 days before study start

Have received antibodies that block the COVID-19 virus

Have active tuberculosis (TB)

Have an active infection (besides COVID-19)

Require a ventilator at study entry

Have cancer

Have a history of more than one blood clot or a blood clot within 12 weeks before entering study

Be pregnant or breastfeeding

Trial Summary

Conditions the trial is for

COVID-19 (Coronavirus)

What the trial is testing?

Baricitinib

Could I receive a Placebo?

yes

Enrollment Goal

1400

Trial Dates

June 2020 - June 2021

Trial Phase

3

Enter your postal code to find the nearest site

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

All

Participants must

Be hospitalized with coronavirus (SARS-COV-2)

Need oxygen therapy when they enter the study and when assigned to treatment

Participants must NOT

Have ever received convalescent plasma or intravenous immunoglobulin [IVIg]) for COVID-19

Have received greater than 20 milligrams per day of oral corticosteroids for more than 14 days before study start

Have received antibodies that block the COVID-19 virus

Have active tuberculosis (TB)

Have an active infection (besides COVID-19)

Require a ventilator at study entry

Have cancer

Have a history of more than one blood clot or a blood clot within 12 weeks before entering study

Be pregnant or breastfeeding

Trial Summary

Conditions the trial is for

COVID-19 (Coronavirus)

What the trial is testing?

Baricitinib

Could I receive a Placebo?

yes

Enrollment Goal

1400

Trial Dates

June 2020 - June 2021

Trial Phase

3

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Trial Locations

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COVID-19 (Coronavirus) Resources

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A clinical trial is a scientific study in people that helps to determine if and how a drug or therapy works. These can also be called clinical studies, or clinical research. Clinical research helps us answer specific questions about an investigational drug , such as: Is it effective? Is it more effective than another established treatment? Is it safe and/or what are its side effects?