Completed

A Study of Ramucirumab (LY3009806) Plus MEDI4736 in Participants With Advanced Gastrointestinal or Thoracic Malignancies

I4T-MC-JVDJ - ClinicalTrials.gov - NCT02572687

The main purpose of this study is to evaluate the safety of ramucirumab plus MEDI4736 in participants with locally advanced and unresectable or metastatic gastrointestinal or thoracic malignancies including gastric or gastroesophageal junction (GEJ) adenocarcinoma, non-small cell lung cancer (NSCLC), or hepatocellular carcinoma (HCC)
How long will I be in the trial?
Your participation could range from several months to several years depending on how you and your tumor respond
Email
Completed

A Study of Ramucirumab (LY3009806) Plus MEDI4736 in Participants With Advanced Gastrointestinal or Thoracic Malignancies

I4T-MC-JVDJ - ClinicalTrials.gov - NCT02572687

The main purpose of this study is to evaluate the safety of ramucirumab plus MEDI4736 in participants with locally advanced and unresectable or metastatic gastrointestinal or thoracic malignancies including gastric or gastroesophageal junction (GEJ) adenocarcinoma, non-small cell lung cancer (NSCLC), or hepatocellular carcinoma (HCC)
How long will I be in the trial?
Your participation could range from several months to several years depending on how you and your tumor respond
Email

Key Requirements

Age :

18+

Sex:

All

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

All

Participants must

Participant must have measurable metastatic disease or locally advanced and unresectable disease

Participant must be willing to provide tumor tissue for biomarker analysis

Participants must NOT

Participant must not have known brain metastases

Participant must not have active or prior documented autoimmune disease within the past 24 months

Participant must not have HIV, AIDS-related illness, or a history of immunodeficiency

Participant with hepatitis B or hepatitis C infection may not be eligible depending on your tumor type

Trial Summary

Conditions the trial is for

Gastroesophageal Junction Cancer (GEJ), Non-small Cell Lung Cancer, Esophageal Cancer, Stomach Cancer

What the trial is testing?

Ramucirumab (LLY3009806) + MEDI4736

Could I receive a Placebo?

no

Enrollment Goal

114

Trial Dates

February 2016 - January 2021

Trial Phase

1

Enter your postal code to find the nearest site

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

All

Participants must

Participant must have measurable metastatic disease or locally advanced and unresectable disease

Participant must be willing to provide tumor tissue for biomarker analysis

Participants must NOT

Participant must not have known brain metastases

Participant must not have active or prior documented autoimmune disease within the past 24 months

Participant must not have HIV, AIDS-related illness, or a history of immunodeficiency

Participant with hepatitis B or hepatitis C infection may not be eligible depending on your tumor type

Trial Summary

Conditions the trial is for

Gastroesophageal Junction Cancer (GEJ), Non-small Cell Lung Cancer, Esophageal Cancer, Stomach Cancer

What the trial is testing?

Ramucirumab (LLY3009806) + MEDI4736

Could I receive a Placebo?

no

Enrollment Goal

114

Trial Dates

February 2016 - January 2021

Trial Phase

1

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Trial Locations

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Resources

Clinical Trial Participation: What to Expect

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study in people that helps to determine if and how a drug or therapy works. These can also be called clinical studies, or clinical research. Clinical research helps us answer specific questions about an investigational drug , such as: Is it effective? Is it more effective than another established treatment? Is it safe and/or what are its side effects?