Recruiting

A Study of LY3454738 in Healthy Participants and Participants With Atopic Dermatitis (Eczema)

J1B-MC-FRCC - ClinicalTrials.gov - NCT03750643

The main purpose of this study is to investigate the safety, tolerability, and efficacy of the study drug known as LY3454738 in healthy participants and participants with atopic dermatitis (eczema). The study has three parts. Each participant will enroll in one part. The study will last 12 to 24 weeks, depending on part.
How long will I be in the trial?
The study will last up to 24 week and may include up to 12 visits.
Email
Recruiting

A Study of LY3454738 in Healthy Participants and Participants With Atopic Dermatitis (Eczema)

J1B-MC-FRCC - ClinicalTrials.gov - NCT03750643

The main purpose of this study is to investigate the safety, tolerability, and efficacy of the study drug known as LY3454738 in healthy participants and participants with atopic dermatitis (eczema). The study has three parts. Each participant will enroll in one part. The study will last 12 to 24 weeks, depending on part.
How long will I be in the trial?
The study will last up to 24 week and may include up to 12 visits.
Email

Key Requirements

Age :

18-65

Sex:

All

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18-65

Sex

All

Participants must

Participants must weigh at least 110 pounds (50 kilograms) - Japanese participants must have all biological parents and grandparents born in Japan and be of exclusive Japanese descent

Participants with atopic dermatitis (AD) must have a diagnosis of AD for at least 12 months. The disease symptoms must be severe enough that they do not respond well to medicines that are applied to the skin

Participants with AD must agree to use moisturizer daily

Participants must NOT

Participants must not have received certain “biologic” medications in a specific time frame. This will be discussed with the study doctor.

Participants with AD must not have received steroids (except those applied to the skin) in the past 6 weeks prior to randomization

Trial Summary

Conditions the trial is for

Atopic Dermatitis (Eczema)

What the trial is testing?

LY3454738 - injected into a vein, LY3454738 - injected just below the skin, Placebo

Could I receive a Placebo?

yes

Enrollment Goal

64

Trial Dates

November 2018 - August 2021

Trial Phase

1

Enter your postal code to find the nearest site

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18-65

Sex

All

Participants must

Participants must weigh at least 110 pounds (50 kilograms) - Japanese participants must have all biological parents and grandparents born in Japan and be of exclusive Japanese descent

Participants with atopic dermatitis (AD) must have a diagnosis of AD for at least 12 months. The disease symptoms must be severe enough that they do not respond well to medicines that are applied to the skin

Participants with AD must agree to use moisturizer daily

Participants must NOT

Participants must not have received certain “biologic” medications in a specific time frame. This will be discussed with the study doctor.

Participants with AD must not have received steroids (except those applied to the skin) in the past 6 weeks prior to randomization

Trial Summary

Conditions the trial is for

Atopic Dermatitis (Eczema)

What the trial is testing?

LY3454738 - injected into a vein, LY3454738 - injected just below the skin, Placebo

Could I receive a Placebo?

yes

Enrollment Goal

64

Trial Dates

November 2018 - August 2021

Trial Phase

1

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Trial Locations

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Atopic Dermatitis (Eczema) Resources

Clinical Trial Participation: What to Expect

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study in people that helps to determine if and how a drug or therapy works. These can also be called clinical studies, or clinical research. Clinical research helps us answer specific questions about an investigational drug , such as: Is it effective? Is it more effective than another established treatment? Is it safe and/or what are its side effects?