Completed Enrollment

Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations

The main purpose of this study is to learn more about the safety, side effects, and early effectiveness of LY3410738. LY3410738 may be used to treat solid cancer tumors that have a change in a particular gene (known as the IDH gene).

Trial Summary

Age Range
≥18 years
Conditions the trial is for
Advanced Solid Tumor
What the trial is testing?
LY3410738
Could I receive a Placebo?
No
Enrollment Goal
200
Trial Dates
Oct 16, 2020 - May 2024
How long will I be in the trial?
Participation could last up to 2 years and possibly longer if the disease does not get worse.
Trial Phase
I

Key Requirements

Clinical trials have inclusion and exclusion requirements to determine which individuals qualify for participation. Listed below are key requirements for this clinical trial, but there may be additional requirements to qualify.

Participants Must:

  • Have an advanced solid tumor cancer with a change in the IDH1 or IDH2 gene

  • Have stopped cancer treatment

  • Be well enough to perform their own personal care

  • Have adequate organ function and blood counts, as measured by blood tests

Participants Must Not:

  • Have an active infection or any serious medical conditions (other than cancer)

  • Have cancer that has spread to the brain or spinal cord and is causing symptoms

  • Have any problems absorbing food or medicine taken by mouth

  • Be taking certain medicines that affect how fast the study drug is broken down in the body

  • Be pregnant or breast-feeding during the study or within 90 days after the last dose of study drug

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