Recruiting

Study of LY3410738 in Patients with Advanced Solid Cancer Tumors with a Change in the IDH1 or IDH2 Gene

I9Y-OX-JDHC - ClinicalTrials.gov - NCT04521686

The main purpose of this study is to learn more about the safety, side effects, and early effectiveness of LY3410738. LY3410738 may be used to treat solid cancer tumors that have a change in a particular gene (known as the IDH gene).
How long will I be in the trial?
Participation could last up to 2 years and possibly longer if the disease does not get worse.
Email
Recruiting

Study of LY3410738 in Patients with Advanced Solid Cancer Tumors with a Change in the IDH1 or IDH2 Gene

I9Y-OX-JDHC - ClinicalTrials.gov - NCT04521686

The main purpose of this study is to learn more about the safety, side effects, and early effectiveness of LY3410738. LY3410738 may be used to treat solid cancer tumors that have a change in a particular gene (known as the IDH gene).
How long will I be in the trial?
Participation could last up to 2 years and possibly longer if the disease does not get worse.
Email

Key Requirements

Age :

18+

Sex:

All

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

All

Participants must

Have an advanced solid tumor cancer with a change in the IDH1 or IDH2 gene

Have stopped cancer treatment

Be well enough to perform their own personal care

Have adequate organ function and blood counts, as measured by blood tests

Participants must NOT

Have an active infection or any serious medical conditions (other than cancer)

Have cancer that has spread to the brain or spinal cord and is causing symptoms

Have any problems absorbing food or medicine taken by mouth

Be taking certain medicines that affect how fast the study drug is broken down in the body

Be pregnant or breast-feeding during the study or within 90 days after the last dose of study drug

Trial Summary

Conditions the trial is for

Sarcoma, Advanced Cancer, Biliary Tract Cancer, Solid Tumor, Brain Cancer

What the trial is testing?

LY3410738

Could I receive a Placebo?

no

Enrollment Goal

180

Trial Dates

October 2020 - February 2023

Trial Phase

1

Enter your postal code to find the nearest site

Key Requirements

Use the following checklist to help determine if this trial may be a good fit for you. Place a checkmark next to each criteria that you successfully meet.

Age

18+

Sex

All

Participants must

Have an advanced solid tumor cancer with a change in the IDH1 or IDH2 gene

Have stopped cancer treatment

Be well enough to perform their own personal care

Have adequate organ function and blood counts, as measured by blood tests

Participants must NOT

Have an active infection or any serious medical conditions (other than cancer)

Have cancer that has spread to the brain or spinal cord and is causing symptoms

Have any problems absorbing food or medicine taken by mouth

Be taking certain medicines that affect how fast the study drug is broken down in the body

Be pregnant or breast-feeding during the study or within 90 days after the last dose of study drug

Trial Summary

Conditions the trial is for

Sarcoma, Advanced Cancer, Biliary Tract Cancer, Solid Tumor, Brain Cancer

What the trial is testing?

LY3410738

Could I receive a Placebo?

no

Enrollment Goal

180

Trial Dates

October 2020 - February 2023

Trial Phase

1

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